Quick Answer: How Fast Should Atropine Be Given?

What is atropine the antidote for?

Atropine is a prescription medicine used to treat the symptoms of low heart rate (bradycardia), reduce salivation and bronchial secretions before surgery or as an antidote for overdose of cholinergic drugs or mushroom poisoning..

How long does IV atropine last?

Intravenous use. Adults: 0.5 – 2 mg atropine sulfate (5 – 20 ml), can be repeated after 5 minutes and subsequently every 10-15 minutes as required, until signs and symptoms disappear (this dose may be exceeded many times).

How do you dilute atropine?

Dilute 1mL of the 600 microgram/mL atropine injection with 5mL sodium chloride 0.9% (to a total volume of 6mL). The resulting solution contains 100microgram/mL atropine. occur easily resulting in respiratory depression requiring ventilation or paralytic ileus requiring IV therapy. Do not mix with sodium bicarbonate.

How fast does atropine work?

Its pharmacological effects are due to binding to muscarinic acetylcholine receptors. It is an antimuscarinic agent. Significant levels are achieved in the CNS within 30 minutes to 1 hour and disappears rapidly from the blood with a half-life of 2 hours.

Why is atropine given?

Atropine is used to help reduce saliva, mucus, or other secretions in your airway during a surgery. Atropine is also used to treat spasms in the stomach, intestines, bladder, or other organs. Atropine is sometimes used as an antidote to treat certain types of poisoning.

What happens if you give too much atropine?

Excess doses of atropine sulfate may cause side effects such as palpitations, dilated pupils, difficulty swallowing, hot dry skin, thirst, dizziness, restlessness, tremor, fatigue, and problems with coordination.

How do you give atropine IV push?

Administer Atropine 0.5 mg IV repeating every 3-5 minutes to a total dose of 3 mg IV, until a heart rate of greater than 60/minute is reached. 3. Transcutaneous pacing (TCP) when available may be initiated prior to establishment of IV access and/or before Atropine begins to take effect.

What is the action of atropine?

Pharmacodynamics. Atropine reduces secretions in the mouth and respiratory passages, relieves the constriction and spasm of the respiratory passages, and may reduce the paralysis of respiration, which results from actions of the toxic agent on the central nervous system.

When should you not take atropine?

Who should not take Atropine SULFATE Syringe?overactive thyroid gland.myasthenia gravis.a skeletal muscle disorder.closed angle glaucoma.high blood pressure.coronary artery disease.chronic heart failure.chronic lung disease.More items…

How is atropine poisoning treated?

Specific treatmentGive physostigmine salicylate, 0.5–1 mg intravenously slowly over 5 minutes, with ECG monitoring.Repeat as needed to total dose of no more than 2 mg.

When should atropine be administered?

Atropine is the first-line therapy (Class IIa) for symptomatic bradycardia in the absence of reversible causes. Treatments for bradydysrhythmias are indicated when there is a structural disease of the infra-nodal system or if the heart rate is less than 50 beats/min with unstable vital signs.

How many doses of atropine can you give?

1 mg IV every 3 to 5 minutes as needed up to a maximum total dose of 3 mg. Clinical practice guidelines do not include atropine due to unlikely therapeutic benefit in pulseless electrical activity (PEA) or asystole. Previously, atropine could be given via the intraosseous route when IV access was not available.