Quick Answer: Is It Better To Be Her2 Positive Or Negative?

Is chemo necessary for her2 positive?

Many studies have shown that these treatments dramatically improve survival for women with HER2-positive breast cancer.

Trastuzumab and chemotherapy are even recommended for women with very small, HER2-positive breast cancers.

Tumors as small as 0.5 cm often warrant such treatment..

What is the most aggressive type of breast cancer?

The most aggressive breast cancers include: Triple-negative breast cancer: This type of breast cancer tests negative for the hormones estrogen and progesterone, and the protein HER2. Inflammatory breast cancer: This rare form of cancer is named because it causes breast swelling and redness.

What is her2 status?

HER2 status. HER2 (human epidermal growth factor receptor 2) is a protein that appears on the surface of some breast cancer cells. It may also be called HER2/neu or ErbB2. The HER2 protein is an important part of the pathway for cell growth and survival. HER2-positive breast cancers have a lot of HER2 protein.

Is her2 negative breast cancer curable?

The 5-year survival rate for stage 1 triple-negative breast cancer is 85%. These cancers tend to grow more quickly and respond to fewer treatments. Sometimes, breast cancers spread, or metastasize, to other parts of the body. Metastatic cancer has a much poorer prognosis.

Does her2 negative change positive?

In some cases the hormone receptor status or HER2 status changed from positive to negative. In other cases the hormone receptor status or HER2 status changed from negative to positive. These changes would definitely affect treatment choices.

What foods should her2 positive avoid?

Foods to avoid if you have HER2-positive breast cancerSugary foods include refined or simple carbohydrates or starches. … Eating too many saturated fats can raise your cholesterol levels. … A 2014 study found that a high-fat diet is strongly linked to HER2-positive breast cancer.

What is the best treatment for her2 positive breast cancer?

Hurvitz: The standard of care to treat curable HER2-positive breast cancer has been to give chemotherapy with the HER2-targeted monoclonal antibody trastuzumab, which was the first drug approved for HER2-positive disease.

Is it better to be ER PR positive or negative?

Hormone Receptor-Positive Breast Cancer If your breast cancer has a significant number of receptors for either estrogen or progesterone, it’s considered hormone-receptor positive. Tumors that are ER/PR-positive are much more likely to respond to hormone therapy than tumors that are ER/PR-negative.

What causes her2 positive breast cancer?

In about 25 percent of breast cancers, the cancer cells have an excess of the HER2 protein. This is caused by a mutation in the HER2 (human epidermal growth factor receptor 2) gene. When the HER2 gene mutates, it causes cells in the breast to grow and divide at an uncontrolled rate, leading to tumor growth.

Is her2 negative breast cancer genetic?

HER2 gene defects, known as “mutations,” develop sometime during your life. Researchers aren’t sure exactly what causes these mistakes to happen. There are other kinds of mutations linked to breast cancer that you can inherit from your parents. If this happens, it doesn’t mean you’ll definitely develop breast cancer.

What does ER positive and her2 negative mean?

Those with progesterone receptors are referred to as PR-positive (or PR+). In addition to hormone receptors, some breast cancers have high levels of a growth-promoting protein called HER2/neu. If a tumor has this property, it is called HER2-positive. HER2 positive cancers are more aggressive than HER2 negative cancer.

Is her2 positive good?

About 25% of breast cancers are HER2-positive. HER2-positive cancers are a mix of good and bad news. The bad news is the tumors tend to grow more aggressively than those without the HER2 receptor. The good news is that like ER/PR-positive cancers, medicines can switch the HER2 growth receptor off.

What does it mean to be her2 negative?

When a breast cell has abnormally high levels of the HER2 gene or the HER2 protein, it is called HER2- positive. The cancer is called HER2-negative when it does not have high levels of the HER2 gene or the HER2 protein. Most patients with metastatic breast cancer have HER2-negative breast cancer.

What is the survival rate of her2 positive breast cancer?

“For most patients with stage I HER2-positive breast cancer, taxane plus trastuzumab remains the standard of care, with excellent 7-year disease-free survival rates of about 93%. For most stage II to III HER2-positive breast cancers, trastuzumab/pertuzumab-based therapy has become a standard option.

Does her2 positive breast cancer come back?

HER2-positive breast cancer is more aggressive and more likely to recur than HER2-negative breast cancer. Recurrence can happen any time, but it usually takes place within 5 years of treatment. The good news is that recurrence is less likely today than ever before. This is largely due to the latest targeted treatments.